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Dermatomyositis with follicular hyperkeratosis
X de la Tribonnière1, E Delaporte, S Alfandari
1Department of Infectious Diseases, University Hospital Center, Tourcoing, France.
Dermatology (Basel, Switzerland)
|January 1, 1995
Summary
Follicular hyperkeratosis (FHK) can occur in children with dermatomyositis, appearing before, during, or after the disease. This condition, though once thought rare in Western countries, may be more common than previously reported.
Area of Science:
- Pediatric Rheumatology
- Dermatology
Background:
- Dermatomyositis is an idiopathic inflammatory myopathy affecting muscles and skin.
- Follicular hyperkeratosis (FHK) is a dermatological condition characterized by excessive keratin buildup in hair follicles.
Observation:
- Two pediatric cases of dermatomyositis with concurrent FHK are presented: a 10-year-old Vietnamese girl and a 9-year-old Caucasian boy.
- The girl's FHK resolved within two months of treatment.
- The boy experienced generalized FHK for six months, starting 15 months after his dermatomyositis diagnosis.
Findings:
- Follicular hyperkeratosis can manifest at any stage of childhood dermatomyositis (preceding, concurrent, or subsequent).
- FHK in dermatomyositis can be generalized or localized.
- Potential underlying mechanisms include erector pili myositis and ostial hyperkeratosis.
Implications:
- The prognostic significance of FHK in pediatric dermatomyositis remains undetermined.
- This case series suggests FHK in dermatomyositis may be underdiagnosed in Western populations.
- Further research is needed to understand the prevalence and clinical implications of FHK in pediatric dermatomyositis.