Delay of pattern electroretinogram peaks and its correlation to contrast threshold for motion perception in glaucoma

Peak latencies of pattern electroretinogram (PERG) were compared between glaucomatous eyes and non-glaucomatous eyes. Contrast threshold for motion perception (CTMP) was also measured with a new device in addition to routine static contrast sensitivity, static visual field and visual acuity. In the present recording, configurations for PERG, i.e. low reversal rate, low mean luminance and presence of background illumination, the PERG peak and trough (P1 and N2, respectively) latencies, were significantly prolonged in the glaucomatous eyes. Although both of the two PERG latencies were strongly correlated with the CTMP, only the P1 peak latency was strongly correlated with the perimetric indices. These results suggest that the P1 and N2 latencies reflect different aspects of signal processing in the retina, especially for moving targets.