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[Destructive arthritis of the hip in Crohn disease. 10 cases]
C Beauvais1, J L Le Quintrec, A Prier
1Service de Rhumatologie, Hôpital Saint-Antoine, Paris.
Insights
Destructive hip arthritis is a rare Crohn's disease complication (2% prevalence). This condition causes significant functional impairment, often requiring interventions beyond standard treatments for inflammatory bowel disease.
Area of Science:
- Rheumatology
- Gastroenterology
- Inflammatory Bowel Disease
Context:
- Crohn's disease (CD) is a chronic inflammatory condition.
- Destructive arthritis of the hip is an uncommon manifestation of CD.
- Understanding its frequency and characteristics is crucial for patient management.
Purpose:
- To determine the prevalence of destructive hip arthritis in Crohn's disease patients.
- To describe the clinical features and course of this complication.
- To compare it with spondylarthritis and assess treatment outcomes.
Summary:
- A 2% prevalence of destructive hip arthritis was observed in 100 Crohn's disease patients.
- Affected patients exhibited joint space narrowing, bone condensation, osteophytosis, and destruction.
- Clinical manifestations mimicked those of idiopathic ankylosing spondylarthritis.
Impact:
- Destructive hip arthritis in CD patients leads to severe functional disability.
- Standard treatments for inflammatory bowel disease and anti-inflammatory drugs were often ineffective.
- Synoviorthesis provided relief in most cases, while three patients required total hip replacement.
Objectives:
Destructive arthritis of the hip joint is a rare manifestation of Crohn's disease. We evaluated its frequency and clinical features in comparison with spondylarthritis and assessed the clinical course.
Methods:
One hundred patients with Crohn's disease were followed prospectively in search of destructive arthritis of the hip joint. Patients with both Crohn's disease and manifestations of inflammatory joint disease hospitalized in three rheumatology units were also evaluated retrospectively.
Results:
The prevalence of destructive hip disease was 2% in patients with Crohn's disease. Ten patients had destructive arthritis of the hip. Three had ankylosing spondylitis, 5 had spondylarthritis not responding to the criteria of ankylosing spondylitis and 2 had no axial joint disease. In all patients, signs of hip joint disease were a narrowed intra-articular space, bone condensation, osteophytosis and features of joint destruction. Manifestations were similar to those in patients with hip joint disease related to idiopathic ankylosing spondylarthritis. The clinical course was poorly controlled by anti-inflammatory drugs or treatment of the inflammatory bowel disease. Synoviorthesis were required and were effective in most cases. Total hip replacement was required in 3 cases.
Conclusion:
Destructive arthritis of the hip in patients with Crohn's disease is a rare complication causing severe functional impairment further handicapping the patient with a chronic bowel disease.