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Updated: Jul 26, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
Myocardial microcirculation as evaluated with CT
1Department of Beijing Heart, Lung and Blood Vessel Medical Center, Beijing Anzhem Hospital, China.
Abstract:
This study explores use of whole-body CT imaging to separately quantitate the physiological behavior of the nonrecruitable (e.g., arterioles) and recruitable (mostly capillary) components of the intramyocardial microcirculation. In two groups of dogs, one with microembolization and one with epicardial artery stenosis, we demonstrate that intramyocardial blood volume (rho) and blood flow (F) follow the relationship rho = AF + BF1/2 where A represents the transit time of the recruitable and BF-1/2 is the transit time of the nonrecruitable components. These transit times are shown to change in different, but characteristic, patterns.
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