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Brainstem auditory evoked potentials in patients with ischemic heart disease
D G Karamitsos1, N G Kounis, G M Zavras
1HIPPOKRATES Otological Center of Patras, Greece.
Insights
Brainstem auditory evoked potentials (BAEPs) were prolonged in patients with ischemic heart disease (IHD), indicating potential microcirculation impairment. This noninvasive method may aid in IHD detection.
Area of Science:
- Neuroscience
- Cardiology
- Audiology
Background:
- Ischemic heart disease (IHD) affects cardiovascular health.
- Early detection of microcirculation impairment in IHD is crucial.
- Brainstem auditory evoked potentials (BAEPs) assess auditory pathway function.
Purpose of the Study:
- To investigate BAEPs in patients with IHD.
- To determine if BAEPs can detect microcirculation abnormalities in IHD.
Main Methods:
- Utilized increased stimulus rate for BAEP recording.
- Recorded BAEPs in 30 IHD patients and 30 healthy controls.
- Measured absolute and interpeak latencies, and peak amplitudes of BAEP waves.
Main Results:
- Significantly increased absolute and interpeak latencies in IHD patients.
- Diminished peak amplitudes observed in IHD patients.
- No significant hearing loss detected in IHD patients via audiometry.
Conclusions:
- This study first demonstrates prolonged BAEPs in IHD patients.
- Altered BAEPs suggest impaired auditory pathway function in IHD.
- BAEP recording shows promise as a noninvasive tool for detecting IHD-related microcirculation issues.
Abstract:
The authors of this study used the method of increased stimulus rate on brainstem auditory evoked potentials (BAEPs) in 30 patients with ischemic heart disease (IHD) and in an equal number of healthy age-matched control subjects. The BAEPs were recorded using 100- to 3000-Hz alternating polarity clicks at a rate of 22.6 per second. Measurements included the absolute latencies of waves I through V, the interpeak latencies I-III, III-V, and I-V, and the peak amplitudes of peaks I, III, and V. The measured absolute latencies and interpeak latencies were found to be significantly increased, and the peak amplitudes were found to be diminished. The audiometric tests revealed no significant hearing loss in IHD patients. This study is the first to demonstrate prolongation of BAEPs in IHD patients. BAEP recording may become an additional noninvasive tool for detecting IHD patients with impaired microcirculation.