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MR pulsatility measurements in peripheral arteries: preliminary results
B Krug1, H Kugel, U Harnischmacher
1Department of Radiology, University of Cologne, Köln-Lindenthal, Germany.
Magnetic Resonance in Medicine
|November 1, 1995
Summary
Phase contrast imaging reveals that flattened flow velocity patterns in arteries correlate with the severity of arteriosclerotic disease. This non-invasive technique aids in assessing peripheral artery disease progression.
Area of Science:
- Vascular Imaging
- Cardiovascular Physiology
- Medical Diagnostics
Background:
- Arteriosclerotic disease, a leading cause of morbidity, affects arterial blood flow.
- Accurate assessment of arterial stenosis severity is crucial for patient management.
- Non-invasive imaging techniques are needed to evaluate blood flow dynamics.
Purpose of the Study:
- To investigate the utility of phase contrast flow velocity measurements in assessing arteriosclerotic disease.
- To correlate quantitative flow velocity parameters with the severity of arterial stenosis.
Main Methods:
- Phase contrast flow velocity measurements were conducted in the iliac and femoral arteries of healthy volunteers and patients with arteriosclerotic disease.
- Data acquisition strategies were optimized to capture full cardiac cycles without gaps.
- Flow velocity patterns were analyzed for systolic acceleration, postsystolic deceleration, and pulsatility.
- Stenosis severity was graded using digital subtraction angiography (DSA).
Main Results:
- Flattening of flow velocity patterns demonstrated a correlation with the local severity of arteriosclerotic disease.
- Quantitative analysis of flow dynamics provided insights into the impact of stenosis on blood flow.
Conclusions:
- Phase contrast flow velocity measurements are a valuable tool for non-invasively assessing the severity of arteriosclerotic disease.
- The study highlights the potential of flow pattern analysis in diagnosing and monitoring peripheral artery disease.