Related Experiment Video
Updated: Aug 27, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
Published on: August 18, 2022
Circumscribed pigmented lesions
1Department of Dermatology, Royal Alexandra Hospital for Children, Camperdown, New South Wales.
Insights
This article discusses common skin pigmentation changes in infants during the first six months of life. It covers various brown and blue pigmentations that can appear as spots or lines.
Area of Science:
- Pediatrics
- Dermatology
- Neonatology
Background:
- Common skin, hair, and nail issues are prevalent in newborns.
- Pigmentation changes are a frequent concern for parents and clinicians.
Purpose of the Study:
- To address skin pigmentation changes in infants up to six months old.
- To describe the appearance and characteristics of these common neonatal skin findings.
Main Methods:
- Review of common dermatological conditions in neonates.
- Clinical description of pigmentation variations observed in infants.
Main Results:
- Identified common skin pigmentation changes in infants.
- Described variations including circumscribed and linear patterns.
- Noted pigmentations appearing as brown or blue.
Conclusions:
- Understanding neonatal pigmentation variations is crucial for appropriate clinical assessment.
- Early identification of benign pigmentation changes can alleviate parental concerns.
Abstract:
In this second article of common skin, hair, and nail problems during the first six months of life, issues related to pigmentation changes in the skin are addressed. These changes may be circumscribed or linear in appearance and either brown or blue.
Related Concept Videos
Pleiotropy
Pigmentation
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Photoreceptors and Visual Pathways

