[Follow-up of 52 patients with chronic aggressive hepatitis]

52 patients with histologically proven chronic aggressive hepatitis have been followed up for a mean period of 31 months by regular clinical visits, laboratory controls and liver biopsies. Only patients already with a decompensated liver cirrhosis at the time of the first biopsy had a deteriorating course of the disease. According to our criteria of activity of the disease, only 6 cases needed treatment. 6 patients died during the period of follow-up, 5 of them from malignant tumors.