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Related Experiment Videos

Radiation therapy for localized prostate cancer

W J Taylor, R G Richardson, M D Hafermann

    Cancer
    |March 1, 1979
    PubMed
    Summary

    Intensive pelvic radiation therapy for prostate cancer showed a 57.7% five-year survival rate for Stage C patients. Estrogen therapy did not appear to impact survival outcomes in this patient group.

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    Area of Science:

    • Oncology
    • Radiation Oncology
    • Urologic Oncology

    Background:

    • Intensive local pelvic radiation therapy has been administered to 401 prostate cancer patients since 1965.
    • A study group of 277 patients treated between 1965 and 1975 was analyzed.
    • The cohort included various stages of prostate cancer, with a majority in Stage C.

    Purpose of the Study:

    • To evaluate the outcomes of intensive local pelvic radiation therapy for prostate cancer.
    • To assess the five-year survival rates for different stages, particularly Stage C.
    • To investigate the influence of estrogen therapy on survival in irradiated Stage C patients.

    Main Methods:

    • Retrospective analysis of 277 prostate cancer patients treated from 1965-1975.
    • Categorization of patients by cancer stage (A, B, C, D).
    • Reporting of current treatment techniques including 10 megavolt photon beam and specific field configurations.

    Main Results:

    • The mean age of patients was 67.6 years.
    • The five-year survival rate for the Stage C group was 57.7%.
    • Estrogen therapy showed no apparent influence on the survival of irradiated Stage C patients.

    Conclusions:

    • Intensive pelvic radiation therapy is a viable treatment option for prostate cancer.
    • Stage C prostate cancer patients demonstrated a 57.7% five-year survival rate.
    • Estrogen therapy does not appear to enhance survival in conjunction with radiation for Stage C prostate cancer.

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