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[Induction of polyvalent immunity against Actinobacillus pleuropneumoniae in an experimental rat model]
L Herrera1, E Montiel, M E Rosales
1Facultad de Estudios Superiores-Cuautitlán, UNAM, Laboratorio de Inmunología, Cuautitlán Izcalli, Estado de México.
Abstract:
Using an experimental model of passive immunity in the rat, the immunizing effect of live cells of Actinobacillus pleuropneumoniae serotypes 1, 3, 5, 7, 9 and 12 was tested against a challenge with serotype 1. It was observed that serotypes 5, 7 and 9 induced polyvalent immunity. Additionally, agglutinating antibodies to the homologous and heterologous serotype were titrated in the sera of immunized mothers; the results indicated that groups immunized with serotypes 5, 7 and 9 had higher titers against serotype 1.