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Volume flow estimation using time domain correlation and ultrasonic flowmetry

F Forsberg1, J B Liu, K M Russell

  • 1Department of Radiology, Thomas Jefferson University, Philadelphia, PA, USA.

Ultrasound in Medicine & Biology
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

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Noninvasive CVI-Q accurately measures blood flow in carotid and femoral arteries, showing good agreement with invasive ultrasonic flowmetry, even during simulated stenosis. This technique offers a reliable method for assessing blood flow dynamics.

Area of Science:

  • Cardiovascular Science
  • Medical Imaging Technology
  • Biomedical Engineering

Background:

  • Accurate volumetric blood flow measurement is crucial for diagnosing and managing cardiovascular diseases.
  • Existing methods like ultrasonic flowmetry have limitations, necessitating evaluation of alternative techniques.

Purpose of the Study:

  • To compare the accuracy and agreement of CVI-Q (time domain correlation) and ultrasonic flowmetry for volumetric blood flow measurement.
  • To assess these techniques in both in vitro and in vivo settings, including simulated arterial stenosis.

Main Methods:

  • Simulated carotid and femoral arterial waveforms using a pulsatile flow pump for in vitro testing.
  • In vivo measurements in canine carotid and femoral arteries, with and without induced 90% stenosis.

Related Experiment Videos

  • Simultaneous measurement of instantaneous maximum and mean flow using CVI-Q and ultrasonic flowmetry.

    • Main Results:

    • In vitro: Both methods showed < +/- 5% error for flow rates > 100 mL/min; ultrasonic flowmetry had higher errors at slower flow rates.
    • In vivo: High correlation coefficients (0.73-0.95) and regression slopes near unity were observed between the two techniques.
    • Despite reasonable agreement, in vivo standard deviations ranged from 20% to 28%.

    Conclusions:

    • Noninvasive CVI-Q provides linear and accurate volumetric blood flow measurements in carotid and femoral arteries.
    • CVI-Q demonstrates comparable accuracy to invasive ultrasonic flowmetry, suggesting its potential as a reliable noninvasive diagnostic tool.