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Imaging Studies II: Ultrasonography

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IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
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Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
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Ultrasonography is an imaging technique that uses high-frequency sound waves to visualize the body's internal structures. It is a non-invasive and safe procedure that does not involve the use of ionizing radiation, making it widely used in various medical fields. Ultrasonography is used to study heart function, blood flow in the neck or extremities, certain conditions such as gallbladder disease, and fetal growth and development.
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Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
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Updated: Dec 31, 2025

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
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Transrectal Subharmonic Ultrasound Imaging for Prostate Cancer Detection.

I Gupta1, B Freid1, V Masarapu1

  • 1Thomas Jefferson University, Philadelphia, PA.

Urology
|January 4, 2020
PubMed
Summary
This summary is machine-generated.

Contrast-enhanced subharmonic imaging (SHI) shows promise for detecting prostate cancer (CaP). This study found SHI achieved up to 80% diagnostic accuracy for clinically significant CaP, with targeted biopsies improving detection rates.

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Area of Science:

  • Medical Imaging
  • Oncology
  • Diagnostic Ultrasound

Background:

  • Prostate cancer (CaP) diagnosis relies on imaging and biopsy.
  • Novel imaging techniques are needed to improve detection rates and accuracy.

Purpose of the Study:

  • To evaluate the prostate cancer (CaP) detection rates of contrast-enhanced, transrectal subharmonic ultrasound imaging (SHI).

Main Methods:

  • 50 subjects underwent contrast-enhanced SHI with various Doppler modes and conventional ultrasound.
  • Biopsies were guided by areas of asymmetrical enhancement.
  • Quantitative SHI parameters and receiver operating characteristic (ROC) curve analysis were used.

Main Results:

  • Cancer was detected in 22 of 50 subjects.
  • Targeted biopsy cores were more likely to be positive for clinically significant CaP (odds ratio 1.39, P=.02).
  • SHI demonstrated diagnostic accuracies up to 0.80, with quantitative subharmonic perfusion estimates being the most accurate.

Conclusions:

  • Contrast-enhanced SHI shows potential for detecting clinically significant prostate cancer.
  • This first-in-human study suggests SHI has a diagnostic accuracy of up to 80% for CaP.