Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Alopecia areata in Korea (1982-1994)

B I Ro1

  • 1Department of Dermatology, Yongsan Hospital, College of Medicine, Chung Ang University, Seoul, Korea.

The Journal of Dermatology
|November 1, 1995
PubMed
Summary

This study compared alopecia areata (AA) treatments. Immunotherapy with dinitrochlorobenzene (DNCB) or diphenylcyclopropenone (DPCP) showed better results for extensive AA than triamcinolone acetonide injections.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Medical mycology education for korean dermatologists.

Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology·2001
Same author

Expressions of beta-defensins in human keratinocyte cell lines.

Journal of dermatological science·2001
Same author

Korean Dermatological Association.

The Journal of dermatology·1999
Same author

Itraconazole in the treatment of sporotrichosis: a Korean experience.

Tropical doctor·1995
Same author

Chronic mucocutaneous candidosis.

International journal of dermatology·1988
Same author

Granuloma pyogenicum.

International journal of dermatology·1986

Area of Science:

  • Dermatology
  • Clinical Medicine
  • Immunology

Background:

  • Alopecia areata (AA) is an autoimmune skin condition affecting hair follicles.
  • Understanding AA's clinical patterns and treatment efficacy is crucial for patient management.

Purpose of the Study:

  • To evaluate the clinical manifestations of alopecia areata (AA).
  • To compare the treatment effectiveness of intralesional triamcinolone acetonide injections versus immunotherapy (dinitrochlorobenzene/diphenylcyclopropenone) for AA.

Main Methods:

  • Clinical study of 905 alopecia areata patients over 12 years.
  • Comparison of intralesional triamcinolone acetonide with dinitrochlorobenzene (DNCB) or diphenylcyclopropenone (DPCP) immunotherapy.

Main Results:

  • Alopecia areata (AA) incidence was 1.5% among dermatology outpatients.
  • Higher efficacy of DNCB/DPCP immunotherapy was observed in cases with bald areas exceeding 50 cm², including alopecia totalis and universalis.
  • No significant difference in treatment outcomes between intralesional triamcinolone acetonide and DNCB/DPCP immunotherapy for smaller bald patches (<50 cm²).

Conclusions:

  • Treatment choice for alopecia areata (AA) may depend on the extent of hair loss.
  • Immunotherapy with DNCB or DPCP demonstrates superior efficacy for severe AA cases compared to intralesional triamcinolone acetonide.

Related Experiment Videos