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Organ function during early acute renal failure does not predict survival in long-term intensive care
P Størset1, N Smith-Erichsen, P Vaagenes
1Department of Anaesthesia, Ullevål University Hospital, Oslo, Norway.
Objective:
To examine outcome in relation to organ function variables during early acute renal failure (ARF).
Design:
Retrospective inception cohort.
Setting:
General intensive care unit (ICU).
Patients:
69 consecutive ARF cases verified to have a creatinine clearance below 50 ml/min with no history of previous renal disease.
Main Outcome Measure:
ICU survival.
Measurements And Results:
Septic severity score (SSS), creatinine clearance, thrombocyte count, bilirubin concentration, cardiac inotropic support, PaO2/FIO2 ratio and oliguria were measured. No differences related to outcome were observed in patients surviving more than 7 days after ARF diagnosis. Patients dying within 7 days of ARF had a significantly higher (worse) SSS. Organ dysfunction was established at the time of ICU admission in the majority of cases.
Conclusion:
The organ function variables tested in this study are of limited predictive value during the early stage of ARF.