Related Experiment Videos
Effect of chemotherapy on growth
A L Ogilvy-Stuart1, S M Shalet
1Christie Hospital and Holt Radium Institute, Withington, Manchester, UK.
Acta Paediatrica (Oslo, Norway : 1992). Supplement
|September 1, 1995
Abstract:
Growth restriction has been demonstrated clearly following the treatment of childhood malignancies, even in the absence of irradiation to the hypothalamic-pituitary axis. The use of CT and spinal irradiation in the original treatment of brain tumours has a marked effect on growth. This effect is most profound in children who have received both treatments and cannot be overcome using GH therapy at conventional doses.