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Related Experiment Videos

What's in a face?

R M Winter1

  • 1Mothercare Unit of Clinical Genetics and Fetal Medicine, Institute of Child Health, London, UK.

Nature Genetics
|February 1, 1996
PubMed
Summary
This summary is machine-generated.

Genetic syndromes cause human facial abnormalities and organ defects. This review covers genes mapped or isolated that are crucial for normal craniofacial development.

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Area of Science:

  • Genetics
  • Developmental Biology
  • Clinical Medicine

Background:

  • Human facial abnormalities are often linked to genetic syndromes.
  • These syndromes involve distinct facial features and defects in other organ systems.
  • Genes responsible for these syndromes are critical for normal development.

Purpose of the Study:

  • To review genes associated with craniofacial abnormalities.
  • To consolidate information on mapped or isolated genes involved in facial development.

Main Methods:

  • Literature review of genetic syndromes causing craniofacial abnormalities.
  • Compilation of data on genes that have been mapped or isolated.

Main Results:

  • Identified and reviewed genes implicated in craniofacial development.
  • Detailed the clinical significance of these genetic factors.

    • Conclusions:

    • Genes play a significant role in normal craniofacial development.
    • Understanding these genes is crucial for clinical and research perspectives.