Related Experiment Videos
The varied lifestyles of intracellular pathogens within eukaryotic vacuolar compartments
F Garcia-del Portillo1, B B Finlay
1Departamento de Biología Molecular, Centro de Biología Molecular Severo Ochoa, Facultad de Biología, Universidad Autónoma de Madrid, Spain.
Trends in Microbiology
|October 1, 1995
Abstract:
Many bacterial pathogens and eukaryotic parasites can enter mammalian cells and live intracellularly inside membrane-bound vacuoles. The intravacuolar lifestyle of these pathogens plays a key role in pathogenesis. Understanding the molecular basis of the development of these specialized intracellular compartments is critical to understanding how these organisms cause disease.