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Improvement of scleredema associated with IgA multiple myeloma after chemotherapy
J A Pujol1, M Bueno, M A Fuertes
1Department of Dermatology, Hospital Clinico Universitario, Faculty of Medicine, Zaragoza, Spain.
Clinical and Experimental Dermatology
|March 1, 1995
Abstract:
The presence of a monoclonal gammopathy in patients with chronic scleredema is a recently described, unusual association of unknown significance. There have been very occasional reports of multiple myeloma in such patients. We now report a patient with long-standing scleredema who developed an IgA-kappa multiple myeloma. Once chemotherapy for the myeloproliferative disorder was instituted, scleredema improved significantly, suggesting a pathogenetic link between the two conditions.