Flexural planar xanthomas: report of four cases

Four patients with primary hyperlipoproteinemia, Frederickson's type IIb, were observed to have symmetrical planar xanthomas affecting flexures: finger webs, antecubital and popliteal fossae, axillae, and intergluteal cleft. Other types of xanthomas were also present and serum lipid electrophoresis showed type IIb pattern. We draw attention to the peculiar pattern of symmetrical planar xanthomatosis hitherto described only with type III disease and some forms of normolipemic xanthomatoses.