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[Multiple clear cell acanthomas]

K Fandrey1, S Rabenhorst, R Fedler

  • 1Hautklinik, Städtischen Kliniken, Dortmund.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|December 1, 1995
PubMed
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Multiple clear cell acanthomas, a rare variant of a benign epidermal tumor, can present in diverse body locations. This case highlights the diagnostic challenges and therapeutic considerations for numerous lesions.

Area of Science:

  • Dermatology
  • Oncology

Background:

  • Clear cell acanthoma is a rare, benign epidermal tumor typically presenting as a solitary lesion on the lower legs.
  • Multiple clear cell acanthomas are exceptionally rare and can occur in atypical locations.

Observation:

  • A 52-year-old man developed over 100 clear cell acanthomas across his entire body over two decades.
  • This extensive presentation deviated significantly from the typical solitary, distal leg occurrence.

Findings:

  • Histological diagnosis of clear cell acanthoma is straightforward.
  • Clinical recognition can be challenging, particularly with multiple, widespread lesions.

Implications:

  • This case underscores the importance of considering multiple clear cell acanthomas in the differential diagnosis of widespread skin lesions.

Related Experiment Videos

  • Therapeutic strategies for solitary and multiple clear cell acanthomas require careful consideration.