Related Experiment Videos
[Adverse drug effect notifications by nurses and comparison with cases reported by physicians]
K Sacilotto1, H Bagheri, M Lapeyre-Mestre
1Service de Pharmacologie Clinique, Centre Midi-Pyrénées de Pharmacovigilance, de Pharmacoépidémiologie et d'Informations sur le Médicament, Centre Hospitalier Universitaire, Faculté de Médecine, Toulouse, France.
Summary
Nurses and doctors report different types of adverse drug reactions. Nurses identified more cutaneous side effects and causal relationships, while doctors reported more serious events and specific organ system effects.
Area of Science:
- Pharmacovigilance
- Clinical Pharmacy
- Healthcare Quality
Background:
- Adverse drug reactions (ADRs) are a significant concern in patient safety.
- Understanding reporting patterns by healthcare professionals is crucial for effective ADR detection and management.
Purpose of the Study:
- To compare the characteristics of ADRs reported by hospital doctors and nurses.
- To identify differences in ADR reporting between these two professional groups.
Main Methods:
- Retrospective analysis of ADR reports collected at Toulouse University Hospital from 1992 to 1993.
- Comparison of ADR types, imputability scores, severity, suspected drug classes, and routes of administration between doctor and nurse reports.
Main Results:
- Nurses reported more cutaneous ADRs (50% vs 24%) and higher imputability scores (55% likely vs 46%) than doctors.
- Doctors reported more neuropsychiatric, hepatic, and renal ADRs, and identified more serious ADRs (19% vs 10%).
- Suspected drugs differed, with nurses reporting more anti-infectives and analgesics, and doctors reporting more neurotropic drugs. Route of administration also varied, with nurses reporting more parenteral and doctors more oral ADRs.
Conclusions:
- Significant differences exist in the types and characteristics of ADRs reported by nurses and doctors.
- Nurses' reports provide valuable insights into cutaneous ADRs and causal relationships.
- Doctors' reports highlight serious ADRs and specific organ system effects, complementing overall ADR surveillance efforts.