Related Experiment Videos
[Normolipemic plane xanthoma, monoclonal gammopathy, anti-lipoprotein activity, hypocomplementemia]
P Modiano1, M N Gillet-Terver, S Reichert
1Service de Dermatologie, Hôpital Fournier, Nancy.
Annales De Dermatologie Et De Venereologie
|January 1, 1995
Abstract
Introduction:
Normolipaemic plane xanthomatosis is classically associated with a monoclonal gammapathy.
Case Report:
We observed this association in a 69-year-old woman. This case was particular since anti-lipoprotein activity due to a monoclonal IgG immunoglobulin was found in the serum with abnormal complement fractions. The paraproteinaemia remained stable after a 2-year follow-up.
Conclusion:
This association is remarkable. The anti-lipoprotein activity of the monoclonal protein should be emphasized in light of the immunological processes involved in the pathogenesis of this association.