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Related Experiment Videos

Genetic testing for cancer predisposition: behavioral science issues

C Lerman1, R T Croyle

  • 1Lombardi Cancer Research Center, Georgetown University Medical Center, Washington, D.C. 20007, USA.

Journal of the National Cancer Institute. Monographs
|January 1, 1995
PubMed
Summary
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Genetic testing for cancer predisposition requires strategies for informed decision-making and minimizing psychological harm. Research suggests developing ethical protocols to guide clinical implementation and patient adherence to surveillance.

Area of Science:

  • Genetics
  • Behavioral Science
  • Medical Ethics

Background:

  • Discovery of major cancer susceptibility genes increases demand for clinical genetic testing.
  • Widespread genetic testing necessitates careful consideration of ethical and psychological implications.

Purpose of the Study:

  • To review behavioral research on genetic testing for cancer predisposition.
  • To propose strategies for effective and ethical genetic testing protocols.

Main Methods:

  • Literature review of behavioral research related to genetic testing.
  • Synthesis of findings to inform protocol development.

Main Results:

  • Identified key areas for enhancing informed decision-making.

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  • Highlighted strategies to minimize adverse psychological consequences.
  • Emphasized the importance of promoting adherence to surveillance recommendations.
  • Conclusions:

    • Effective and ethical genetic testing protocols are crucial for managing cancer predisposition.
    • Behavioral research provides a foundation for developing these essential protocols.