Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mosaic evolution of rodent B1 elements

E Zietkiewicz1, D Labuda

  • 1Centre de Cancérologie Charles Bruneau, Hôpital Sainte-Justine, Département de Pédiatrie, Université de Montreal, Québec, Canada.

Journal of Molecular Evolution
|January 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Estimation of the Age of the Kashubian-Specific Pathogenic <i>NPHS2</i> Variant Responsible for Hereditary Steroid-Resistant Nephrotic Syndrome Points to Its Recent Local Origin.

Human mutation·2025
Same author

Transcriptome variation in human populations and its potential application in forensics.

Journal of applied genetics·2019
Same author

Transcriptomic population markers for human population discrimination.

BMC genetics·2018
Same author

EurEAs_Gplex--A new SNaPshot assay for continental population discrimination and gender identification.

Forensic science international. Genetics·2015
Same author

A homozygous mutation in SLC1A4 in siblings with severe intellectual disability and microcephaly.

Clinical genetics·2015
Same author

Identification of chrysanthemum cultivars and stability of DNA fingerprint patterns.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2013
Same journal

Sensing Underwater: Diversifying Selection, Convergent Evolution and Inactivation in Sensory Receptors' Genes of Aquatic Mammals.

Journal of molecular evolution·2026
Same journal

Synonymous Codons as Potential Contributors to Chromatin Stability and Gene Body Methylation in Plants.

Journal of molecular evolution·2026
Same journal

Convergent Functional Genomic Evolution Underlying Repeated Freshwater Colonization in Cetaceans.

Journal of molecular evolution·2026
Same journal

Conditions Enabling the Persistence of Cooperating Synthetase, Ligase, and Mutation-Inhibitor Catalytic Polymers.

Journal of molecular evolution·2026
Same journal

Lineage-Specific Diversification of Nucleoporin Nup98 Genes in Ciliates and Its Evolutionary Implications for the Nuclear Dualism.

Journal of molecular evolution·2026
Same journal

Mitochondrial Genome Evolution: The Influence of Partitioning, Calibration, and Gene Heterogeneity on Pleurodontan Substitution Rates.

Journal of molecular evolution·2026
See all related articles

Researchers analyzed B1 elements in rodents, revealing independent evolution in distinct lineages. These mobile genetic elements exhibit mosaic structures, suggesting a shared evolutionary origin with Alu repeats.

Area of Science:

  • Genetics
  • Molecular Evolution
  • Bioinformatics

Background:

  • B1 elements are repetitive DNA sequences found in rodents.
  • Understanding their evolution provides insights into genome dynamics and speciation.
  • Previous studies suggested potential relationships between different rodent B1 elements.

Purpose of the Study:

  • To determine the sequences of B1 elements in various rodent species.
  • To investigate the phylogenetic relationships of B1 elements across different rodent suborders.
  • To explore the evolutionary origins and structural characteristics of B1 elements.

Main Methods:

  • Polymerase Chain Reaction (PCR) amplification of B1 elements.
  • DNA sequencing of amplified B1 elements.

Related Experiment Videos

  • Phylogenetic analysis using sequence data.

    • Main Results:

    • Identified 3-6 B1 subfamilies in hamsters, rats, chipmunks, and guinea pigs.
    • Phylogenetic analysis showed distinct clustering of B1 sequences from Myomorpha (hamster, rat) and Sciuroidea (chipmunk) and Caviomorpha (guinea pig).
    • Diagnostic characters in B1 quasi-dimers were interpreted as mosaic structures, not convergent mutations, supporting independent evolution in rodent lineages.

    Conclusions:

    • B1 elements have evolved independently in separate rodent lineages.
    • B1 elements are mosaic structures, assembling pre-existing mutations.
    • Structural similarities to Alu repeats support a monophyletic origin for both Alu and B1 elements from a common 7SL RNA-derived element.