Related Experiment Video
Updated: Aug 14, 2026

Controlled Reversible Visceral Arterial Ischemia, Venous Congestion and Combined Malperfusion via Midline Laparotomy in Rats
Published on: July 5, 2024
[Gastroduodenal stress hemorrhage during intensive care]
G Offenstadt1, E Maury, B Guidet
1Service de réanimation polyvalente, Hôpital Saint-Antoine, Paris.
Abstract:
Stress gastric erosions are in fact the gastroduodenal expression of a most disseminated injury involving whole organism. Ischemia represents the main factor leading to the decrease of gastric mucosa protective mechanisms. The most important complication of stress ulceration is acute bleeding. Gastrointestinal hemorrhages of clinical relevance are now so scarce that widespread systematic prophylaxis against stress ulcers can be safely withheld. Supportive therapy of associated acute organ failure remains the most accurate prophylaxis. Patients who are the most likely to benefit from specific prophylaxis are still unknown.
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