[Immunoblastic lymphadenitis: pathohistologic picture and differential diagnosis from malignant lymphoma]

Immunoblastic lymphadenitis is a T-cell immune hyper-response to antigenic stimulation. Patho-histologically, polymorphic hyperplasia of the lymph node pulp with a widening of the paracortical zone and the disturbance of the node structure is found. The cells of the paracortical proliferate are represented by small lymphocytes, stimulated lymphoid cells of varying size with numerous immunoblasts, plasma cells at various stages of maturation including lymphoplasmocytoid ones. When the structure of the lymph node is disturbed immunohistochemical examination is necessary to reject malignant lymphoma.