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[Prognostic value of K-ras gene mutation in colorectal cancer]
J P Cerottini1, J C Givel, J Benhattar
1Centre Hospitalier Universitaire Vaudois, Service de Chirurgie, Lausanne.
Abstract:
Numerous acquired genetical mutations are now well described by molecular biology and seem to be related to tumour progression. K-RAS mutation is of interest in colorectal cancer where it could be correlated to an aggressive tumoral behaviour leading to a high risk of recurrence or metastasis.