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Related Experiment Videos

Blood pressure control during surgical operations

E Furutani1, M Araki, T Sakamoto

  • 1Department of Electrical Engineering, Kyoto University, Japan.

IEEE Transactions on Bio-Medical Engineering
|October 1, 1995
PubMed
Summary

A novel blood pressure control system using a state-predictive controller was developed to reduce intraoperative blood loss. This system demonstrated safety and stability in canine trials, effectively managing mean arterial pressure (MAP).

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Area of Science:

  • Biomedical Engineering
  • Control Systems Engineering
  • Anesthesiology

Background:

  • Intraoperative blood loss and the need for blood transfusions are significant concerns in surgery.
  • Effective blood pressure management is crucial for patient safety and surgical outcomes.

Purpose of the Study:

  • To develop and evaluate a state-predictive controller-based blood pressure control system.
  • To reduce intraoperative blood loss and minimize the requirement for blood transfusions.

Main Methods:

  • A physiological model incorporating pure and first-order delays was derived from experimental data in adult mongrel dogs.
  • A state-predictive servo system was designed to manage mean arterial pressure (MAP) using trimethaphan camsilate infusion.
  • The system's accuracy and reliability were assessed through in-vivo canine experiments.

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Main Results:

  • The system successfully controlled MAP, reaching a reference level of 60 mmHg within 5.8 to 26.5 minutes.
  • The duration of error from the reference MAP (+/- 10%) was minimal, averaging 2.3 +/- 3.9 min/h across seven trials.
  • Experimental results demonstrated the system's safety and stability in maintaining target blood pressure.

Conclusions:

  • The developed state-predictive controller system offers a safe and stable method for blood pressure management during surgery.
  • This technology has the potential to significantly reduce intraoperative blood loss and reliance on blood transfusions.