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Copper-associated liver disease in childhood
A Baker1, S Gormally, R Saxena
1Variety Club Children's Hospital, King's College Hospital, London, UK.
Journal of Hepatology
|November 1, 1995
Summary
Copper-associated liver disease in children presents with rapid liver failure. Early diagnosis and intervention are crucial for better outcomes in this severe pediatric liver condition.
Area of Science:
- Pediatric Hepatology
- Toxicology
- Medical Genetics
Background:
- Indian childhood cirrhosis (ICC) is a severe pediatric liver disease characterized by high copper levels and mortality.
- Early penicillamine treatment has shown promise in reducing mortality and reversing liver damage in ICC.
- The clinical spectrum and diagnosis of copper-associated liver disease outside the Indian subcontinent require further definition.