Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Techniques for measuring renal transit time

C D Russell1, M Japanwalla, S Khan

  • 1Division of Nuclear Medicine and Nuclear Medicine Service, University of Alabama at Birmingham Medical Center, Birmingham, Alabama, USA.

European Journal of Nuclear Medicine
|December 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Orbital-flop transition of superfluid <sup>3</sup>He in anisotropic silica aerogel.

Nature communications·2024
Same author

Magnetic Susceptibility of Andreev Bound States in Superfluid ^{3}He-B.

Physical review letters·2023
Same author

Greener residential environment is associated with increased bacterial diversity in outdoor ambient air.

The Science of the total environment·2023
Same author

Embolism of the Pulmonary Artery in a Horse.

The Journal of comparative medicine and veterinary archives·2022
Same author

Defining resistance and tolerance traits in Covid-19: towards a stratified medicine approach.

QJM : monthly journal of the Association of Physicians·2022
Same author

Effect of Magnetic Impurities on Superfluid ^{3}He.

Physical review letters·2020
Same journal

[Not Available].

European journal of nuclear medicine·2016
Same journal

A Window on Latin America.

European journal of nuclear medicine·2016
Same journal

Erratum: Eur J Nucl Med (1999) 26: 686-692.

European journal of nuclear medicine·2016
Same journal

Nuclear medicine in the next decade.

European journal of nuclear medicine·2014
Same journal

Erratum: Impact of attenuation correction on the accuracy of FDG-PET in patients with abdominal tumors: a free-response ROC analysis.

European journal of nuclear medicine·2014
Same journal

(99m)Tc(V)DMSA quantitatively predicts (188)Re(V)DMSA distribution in patients with prostate cancer metastatic to bone.

European journal of nuclear medicine·2014
See all related articles

Simple renal transit time indices, peak time and R20/3, effectively correlate with kidney pathology. These methods using whole-kidney regions of interest are as effective as complex techniques for quantitative estimation.

Area of Science:

  • Nephrology
  • Nuclear Medicine
  • Radiology

Background:

  • Quantitative estimation of renal transit time is crucial for diagnosing kidney conditions.
  • Various techniques exist, but their comparative efficacy in correlating with renal artery stenosis is not fully established.

Purpose of the Study:

  • To compare different indices of renal transit time for their correlation with angiographic percent of stenosis.
  • To evaluate the effectiveness of simple whole-kidney region of interest (ROI) methods versus complex analysis techniques.

Main Methods:

  • Technetium-99m mercaptoacetyltriglycine (MAG3) renography was performed on 30 patients before arteriography.
  • Indices calculated included peak time, mean transit time, and R20/3 ratio from whole-kidney and cortical ROIs.
  • Factor analysis and deconvolution were used for more complex calculations.

Related Experiment Videos

Main Results:

  • The strongest correlations between angiographic stenosis and transit time indices were observed for whole-kidney peak time and R20/3 ratio.
  • These simple indices showed significant correlation (Spearman's p=0.469, P <0.005) with pathology using baseline data.
  • Simple indices performed comparably to complex methods requiring deconvolution or factor analysis.

Conclusions:

  • Whole-kidney peak time and R20/3 are simple, effective indices for quantitative estimation of renal transit time.
  • These straightforward methods correlate well with renal pathology, offering a practical alternative to complex analyses.
  • The findings support the use of basic transit time indices in clinical settings for assessing kidney function and stenosis.