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Updated: Sep 7, 2026

A Methodological Approach to Non-invasive Assessments of Vascular Function and Morphology
Published on: February 7, 2015
[Comparative study of color Doppler echocardiography and arteriography in carotid disease]
Y Alimi1, B Antetomaso, P Barthelemy
1Service de Chirurgie Vasculaire, Hôpital Nord, Marseille.
Insights
Color duplex scanning is highly sensitive for detecting carotid artery stenosis but less specific than angiography. Angiography remains superior for identifying complex lesions and anatomical variations, guiding selective use in specific patient cases.
Area of Science:
- Vascular Surgery
- Diagnostic Imaging
- Neurology
Background:
- Duplex scanning accuracy has improved, reducing the need for invasive angiography in carotid lesion evaluation.
- Angiography carries significant morbidity, prompting a re-evaluation of its role in diagnosing carotid artery disease.
Purpose of the Study:
- To compare the diagnostic information provided by color duplex scanning and angiography for severe carotid lesions.
- To determine the impact of these imaging modalities on therapeutic decisions for patients with carotid artery disease.
Main Methods:
- A comparative analysis of 122 patients' preoperative color duplex scanning and angiographic results.
- Angiography was used as the reference standard for evaluating carotid artery stenosis and ulcerations.
- Pathologic examination of 94 surgically treated patients was used to assess ulceration detection accuracy.
Main Results:
- Color duplex scanning demonstrated 97% sensitivity and 57% specificity for detecting significant carotid artery stenosis.
- Both methods showed similar accuracy for screening ulcerations, detecting only two-thirds of those found on pathology.
- Angiography was more reliable for detecting carotid artery length variations, internal carotid thrombosis, and dissections in dysplastic arteries.
Conclusions:
- Selective indication of angiography is proposed for suspected proximal periaortic arterial lesions, complications in dysplastic arteries, and pre-thrombotic carotid lesions.
- Angiography is recommended to confirm significant stenosis in asymptomatic patients.
- Color duplex scanning is a valuable, less invasive tool, but angiography retains a crucial role for specific complex carotid artery pathologies.
Abstract:
The increasing accuracy of duplex scanning and the morbidity linked to angiography have led some authors to discard the latter when exploring patients with severe carotid lesions. In order to fully define the respective information obtained by these two explorations and to determine their impact on therapeutic decisions, were examined the file of 122 patients. The comparative analysis of preoperative color duplex scanning and angiographic results, the latter used as a reference, showed a sensitivity of 97% and a specificity of 57%, concerning the ability to detect a significant carotid artery stenosis. On the other hand, color duplex scan and angiography had the same accuracy to screen the presence of an ulceration, but could only detect two third of the ulcerations observed on pathologic examination of 94 surgically-treated patients. At last, angiography was more reliable in detecting a carotid excess of length (p < 0.001), in the identification of internal carotid thrombosis and of dissection on dysplasic arteries. In conclusion, we propose a selective indication of angiography in case of suspicion of proximal periaortic arterial lesions, of complications on dysplastic arteries, of detection of pre-thrombotic carotid lesions and in order to confirm the existence of significant stenosis in asymptomatic patients.
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