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Strategies for the synthesis of some complex antitumor alkaloids
1Organic Chemistry Laboratory, University of Amsterdam, The Netherlands.
Farmaco (Societa Chimica Italiana : 1989)
|November 1, 1995
Abstract:
The total synthesis of sesbanimide A and its analogues has been achieved. The synthesized sesbanimides have been investigated for structure activity relationship. An approach has been developed for the synthesis of the antitumour alkaloid manzamine A. Recent results in these areas will be discussed.