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The glucocorticoid receptor resource

M Danielsen1, E Martinez

  • 1Department of Biochemistry, Georgetown University Medical School, Washington, DC 20007, USA.

Nucleic Acids Research
|January 1, 1996
PubMed
Summary
This summary is machine-generated.

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This resource provides a comprehensive database on glucocorticoid receptor structure-function relationships, including sequence data and electronic publication options for rapid scientific dissemination.

Area of Science:

  • Molecular Biology
  • Genomics
  • Biochemistry

Background:

  • The glucocorticoid receptor (GR) plays a crucial role in cellular regulation.
  • Understanding GR structure-function relationships is vital for biological research.
  • Existing resources may lack integrated data and rapid publication capabilities.

Purpose of the Study:

  • To establish a centralized resource for glucocorticoid receptor (GR) information.
  • To facilitate research on GR structure-function relationships.
  • To enable rapid dissemination of scientific findings on steroid receptors.

Main Methods:

  • Database development integrating sequence and bibliographic information.
  • Inclusion of sequence comparisons across species.

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  • Providing source information for GR-related reagents (clones, probes, cell lines, antibodies).

    • Main Results:

    • A comprehensive online database (http://biochem1.basic-sci.georgetown.edu/grr/grr.html) is available.
    • The database links to sequence and bibliographic data.
    • It includes comparative sequence data and reagent source information.

    Conclusions:

    • The glucocorticoid receptor resource offers a valuable platform for researchers.
    • It supports the study of GR structure-function relationships.
    • The electronic publication feature accelerates scientific communication in the steroid receptor field.