Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Autosomal dominant polycystic kidney disease

D K Beebe1

  • 1University of Mississippi Medical Center, Jackson, Mississippi, USA.

American Family Physician
|February 15, 1996
PubMed
Summary

Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited disorder affecting nearly 500,000 Americans. Management focuses on controlling hypertension and treating complications, with dialysis and transplantation offering successful outcomes for renal failure.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Caring for infants with congenital heart disease and their families.

American family physician·1999
Same author

Sexual assault: the physician's role in prevention and treatment.

Journal of the Mississippi State Medical Association·1998
Same author

Halitosis.

American family physician·1996
Same author

Smokable methamphetamine ('ice'): an old drug in a different form.

American family physician·1995
Same author

Management of common anxiety disorders.

American family physician·1994
Same author

Prevalence of sexual assault among women patients seen in family practice clinics.

Family practice research journal·1994

Area of Science:

  • Nephrology
  • Genetics
  • Internal Medicine

Background:

  • Autosomal dominant polycystic kidney disease (ADPKD) is a prevalent inherited condition in the U.S.
  • Affects approximately 500,000 Americans, contributing 5-10% of end-stage renal disease cases.
  • Typically diagnosed in middle age with complications like hypertension, pain, and hematuria.

Purpose of the Study:

  • To summarize the key aspects of autosomal dominant polycystic kidney disease.
  • To outline common renal and extra-renal manifestations.
  • To discuss current management strategies and treatment outcomes.

Main Methods:

  • Literature review of autosomal dominant polycystic kidney disease.
  • Analysis of disease prevalence and impact on end-stage renal disease.
  • Summary of clinical presentation, complications, and management.

Main Results:

  • ADPKD presents with renal complications (hypertension, cyst infection, hematuria) and other conditions (polycystic liver disease, cerebral aneurysms).
  • Disease course and severity exhibit significant inter-individual variability.
  • Effective management includes hypertension control, complication treatment, and supportive therapies.

Conclusions:

  • ADPKD requires comprehensive management addressing both renal and systemic complications.
  • Genetic counseling is crucial for affected families.
  • Dialysis and renal transplantation are effective for end-stage renal disease secondary to ADPKD.

Related Experiment Videos