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Sulfate-reducing bacteria in the periodontal pocket
J S van der Hoeven1, C W van den Kieboom, M J Schaeken
1Laboratory of Oral Microbiology, Subfaculty of Dentistry, University of Nijmegen, The Netherlands.
Oral Microbiology and Immunology
|October 1, 1995
Summary
Sulfate-reducing bacteria were found in the human mouth for the first time, specifically in subgingival dental plaque. These bacteria, including Desulfobacter and Desulfovibrio genera, may be limited by sulfate availability in the oral environment.
Area of Science:
- Oral microbiology
- Anaerobic bacteria research
- Periodontal disease pathogenesis
Background:
- Sulfate-reducing bacteria (SRB) are known to inhabit the human gut.
- The presence and role of SRB in the oral cavity have not been previously documented.
Purpose of the Study:
- To investigate the occurrence of sulfate-reducing bacteria in human subgingival dental plaque.
- To identify the genera of SRB present in the oral cavity.
Main Methods:
- Collection of subgingival dental plaque samples from individuals.
- Utilized enrichment cultures to detect and isolate sulfate-reducing bacteria.
- Identified bacterial isolates to the genus level.
Main Results:
- Sulfate-reducing bacteria were detected in 58% of individuals and 48% of samples.
- Predominant SRB genera identified were Desulfobacter and Desulfovibrio.
- These genera are also dominant SRB in the human large intestine.
Conclusions:
- This study provides the first evidence of sulfate-reducing bacteria in the human mouth.
- Oral SRB utilize sulfate as a terminal electron acceptor, similar to their gut counterparts.
- Sulfate availability in the subgingival area may limit oral SRB populations.