Human trypanosomiasis in Southern Africa

Five cases of human trypanosomiasis are presented. The clinical picture and course of the disease, and the results of haematological, immunological and other special examinations, are presented. The persistence of decreased total haemolytic complement, increased serum igM levels, decreased plasma fibrinogen levels, raised plasma and urinary fibrinogen split products, cryofibrinogenaemia and significant proteinuria in the presence of apparent clinical cure, tends to indicate the continuation of an immune complex process in spite of eradication of the parasite.