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Updated: Mar 28, 2026

Methionine Functionalized Biocompatible Block Copolymers for Targeted Plasmid DNA Delivery
Published on: August 6, 2019
Hemocompatible properties of polymeric derivative of paracetamol
A A De Queiroz1, A Gallardo, J S Román
1Escola Federal de Engenharia de Itajubá, Departamento de Ciências (ICI), Brazil.
Abstract:
Copolymerization of N,N-dimethylacrylamide (DMAA) and p-acryloyloxiacetanilide (AOA) was carried out at different mole ratios of the monomers to obtain copolymers of varying compositions. DMAA contents were very near to the corresponding monomer feed and varied between 0.20 and 0.80. Investigation of the protein adsorption of these polymer surfaces showed that copolymers with higher DMAA content adsorbed more albumin than fibrinogen. The scanning electron micrographs of the polymer-coated coverslips after contact with blood showed an antithrombogenic behaviour of these surfaces.
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