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Updated: Aug 9, 2026

Rapid Genetic Analysis of Epithelial-Mesenchymal Signaling During Hair Regeneration
Published on: February 28, 2013
Planning for maximum coverage in surgical hair restoration
Background:
Previous articles in this publication have suggested that an isolated frontal forelock is probably the best objective for a majority of patients undergoing hair transplantation.
Objective:
This communication disputes the advisability of an isolated frontal forelock for a majority of hair transplant patients.
Methods:
Previous studies and publications indicate a relatively low incidence of extensive male pattern baldness. Newer harvesting techniques require relatively small donor a areas to yield large numbers of grafts. Alopecia reduction can significantly improve the donor/recipient area ratio, and minigrafting can produce very natural looking results with less donor graft utilization. All of the preceding are presented to support the position of the author.
Results:
Limiting oneself to an isolated frontal forelock is an overly conservative objective for a sizable majority of patients.
Conclusion:
The isolated frontal forelock is a wise goal for a minority of patients who should be chosen on the basis of their limited objectives as well as their family history and a careful physical examination at the time of presentation. For most patients, more extensive coverage remains a reasonable option.

