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Dermatofibrosarcoma protuberans treated with Mohs surgery. A case with CD34 immunostaining variability

C Garcia¹, G Viehman, M Hitchcock

¹Dermatologic Surgery and Cutaneous Oncology Unit, Duke University Medical Center, Durham, North Carolina 27710, USA.

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [Et Al.]

|February 1, 1996

Summary

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CD34 antigen expression in dermatofibrosarcoma protuberans (DFSP) can vary. This variability, particularly in nodular areas, necessitates careful interpretation of immunohistochemical stains during Mohs surgery.

Area of Science:

Oncology
Dermatopathology

Background:

CD34 immunohistochemistry aids in diagnosing dermatofibrosarcoma protuberans (DFSP) and assessing surgical margins.
Variable CD34 expression in DFSP, especially in nodular regions, can lead to diagnostic challenges.

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