Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Post-irradiation malignant mesothelioma

A Cavazza1, L B Travis, W D Travis

  • 1Department of Laboratory Medicine and Pathology, Mayo Clinic Scottsdale, Arizona 85259, USA.

Cancer
|April 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Saccorhiza polyschides used to synthesize gold and silver nanoparticles with enhanced antiproliferative and immunostimulant activity.

Materials science & engineering. C, Materials for biological applications·2021
Same author

Routine antiseptic baths and MRSA decolonization: diverse approaches across Singapore's acute-care hospitals.

The Journal of hospital infection·2021
Same author

Absolutely FABulous? FABP-1 in Non-acetaminophen-related Acute Liver Failure.

Digestive diseases and sciences·2020
Same author

Immunostimulant and biocompatible gold and silver nanoparticles synthesized using the Ulva intestinalis L. aqueous extract.

Journal of materials chemistry. B·2019
Same author

Experience of the implementation and outcomes of universal testing for Lynch syndrome in the United Kingdom.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland·2019
Same author

Histopathology of vasculitis.

Reumatismo·2018
Same journal

Toward exercise as standard care for older cancer survivors.

Cancer·2026
Same journal

Maintenance therapy in gynecologic malignancies: Current and future state.

Cancer·2026
Same journal

Long-term outcomes of evolving treatment regimens in Ewing sarcoma survivors diagnosed 1970-1999: A report from the Childhood Cancer Survivor Study.

Cancer·2026
Same journal

Large-scale osteosarcoma sequencing reveals age-associated genomic architectures.

Cancer·2026
Same journal

EZH2 inhibitor tazemetostat voluntarily withdrawn from market.

Cancer·2026
Same journal

Nivolumab and chemotherapy combination approved for previously untreated Hodgkin lymphoma.

Cancer·2026
See all related articles

Malignant mesothelioma rarely occurs as a second cancer after radiotherapy. A population-based study found temporal and demographic patterns similar to asbestos-related mesotheliomas, suggesting late effects of cancer treatment may contribute.

Area of Science:

  • Oncology
  • Epidemiology
  • Radiation Oncology

Background:

  • Malignant mesothelioma following radiotherapy is rarely reported.
  • Population-based studies on this specific occurrence are lacking.

Purpose of the Study:

  • To investigate the occurrence, temporal patterns, and demographic features of malignant mesothelioma as a second malignant neoplasm after radiotherapy.
  • To compare these features with asbestos-related mesotheliomas.

Main Methods:

  • Collected data on patients with malignant mesothelioma of the pleura who had prior cancer and received radiotherapy.
  • Utilized data from the National Cancer Institute's Surveillance, Epidemiology and End Results Program and the Connecticut Tumor Registry.
  • Conducted a literature review on post-irradiation malignant mesotheliomas.

Related Experiment Videos

Main Results:

  • Identified 8 patients with mesothelioma post-radiotherapy; mean age 45, mean latency 21 years.
  • Epidemiologic survey identified 142 patients; mean age 68.5, median latency 4.3 years.
  • Histological types included epithelial, biphasic, and sarcomatous mesothelioma.

Conclusions:

  • Mesotheliomas are rare second malignant neoplasms.
  • Demographic and temporal patterns of post-radiotherapy mesotheliomas resemble asbestos-related tumors.
  • Late effects of cancer treatment may contribute to secondary mesothelioma development.