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[Ampicillin in high doses in bronchopneumopathies in aged patients]

G Castellani

    Archivio Per Le Scienze Mediche
    |January 1, 1977
    PubMed

    Insights

    Ampicillin effectively treats bronchopneumopathy in 88-90% of patients. This antibiotic is well-tolerated, especially for elderly individuals, and remains a valuable treatment option.

    Area of Science:

    • Pharmacology
    • Infectious Diseases
    • Respiratory Medicine

    Context:

    • Bronchopneumopathy treatment presents challenges.
    • Evaluating antibiotic efficacy and tolerance is crucial.

    Purpose:

    • To assess the effectiveness and tolerance of ampicillin for bronchopneumopathy.
    • To compare oral and intravenous ampicillin administration.

    Summary:

    • Ampicillin administered orally (2-4 g/day) achieved 88% efficacy in 25 bronchopneumopathy cases.
    • Intravenous ampicillin (2 g/12 hr slow drip) showed 90% efficacy in 20 cases.
    • Excellent tolerance was observed in most patients, with only 4 cases reporting adverse effects.

    Impact:

    • Ampicillin remains a highly effective and well-tolerated antibiotic for bronchopneumopathy.
    • It is particularly significant for treating elderly patients.
    • Despite newer antibiotics, ampicillin's established profile supports its continued use.

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