[Ultrastructural signs of differentiation of stomach cancer cells]

Studies of the ultrastructure of stomach cancer were carried out: adenomacarcinoma (4 observations), signet ring cell carcinoma (1 observation), nondifferentiated cancer (1 observation). In 5 out of 6 observations cells of each tumour were homogeneous in principle. Signs of differentiation were revealed in them in a various degree of manifestation in any one direction: according to the type of additional or surface cells in 3 adenocarcinomas; according to that of goblet cells in signet ring cell carcinoma. In the case of nondifferentiated cancer signs of differentiation were absent. In one observation the cells of adenocarcinoma had ultrastructural features of various cells: mucoid, chief, parietal, endocrine, enterocytic, goblet cells. In a part of cancer cells there were noted combined ultrastructural signs of various cells of the gastric mucosa.