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Change in thyroid hormone levels following response to cognitive therapy for major depression
The American Journal of Psychiatry
|March 1, 1996
Abstract
Objective:
Various somatic antidepressant treatments of depression are associated with substantial but limited decreases in T4 levels. This study examined changes in patients' thyroid hormone levels during a period of cognitive behavior therapy.
Method:
Thyroid hormone levels of 30 patients with major depressive disorder were measured before and after they received 20 weekly sessions of cognitive behavior therapy.
Results:
There were significant decreases in measures of T4 in the 17 responders to cognitive behavior therapy and increases in the 13 nonresponders.
Conclusions:
Cognitive behavior therapy has an effect on the thyroid axis similar to that of somatic antidepressant treatments.