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Related Experiment Videos

Development and evaluation of a shipping system for platelet components

V M George1, T C Pringle, L Kline

  • 1Product Development Department, American Red Cross Holland Laboratory, Rockville, Maryland 20855, USA.

Transfusion
|April 1, 1996
PubMed
Summary

A new insulated shipping container system effectively maintains platelet component temperatures during transport. Temperature stabilizing packs significantly enhance performance, ensuring component quality and meeting shipping needs.

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Area of Science:

  • Biomedical Engineering
  • Blood Product Logistics
  • Materials Science

Background:

  • Maintaining platelet concentrates and apheresis platelets within 20-24°C during transport is critical.
  • Current transport methods face challenges in precise temperature control.
  • Ensuring component quality necessitates improved temperature management during transit.

Purpose of the Study:

  • To evaluate a novel insulated shipping container system for platelet transport.
  • To assess the system's ability to maintain target temperatures under various ambient conditions.
  • To determine the impact of temperature stabilizing packs (TSPs) on thermal stability.

Main Methods:

  • Molded polyurethane-insulated containers were used with simulated platelet components.

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  • Experiments included payloads with and without gel-based TSPs.
  • Containers were exposed to constant ambient temperatures of 37°C, 4°C, and -10°C for 24 hours.
  • Payload temperatures were continuously monitored in situ.
  • Main Results:

    • At 37°C, payloads with TSPs took 6.1-6.9 hours to increase by 1°C, compared to 2.5-3.8 hours without TSPs.
    • At 4°C, payloads with TSPs took 4.6-5.6 hours to decrease by 1°C, versus 1.8-3.4 hours without TSPs.
    • At -10°C, payloads with TSPs took 2.7-2.9 hours to drop by 1°C, compared to 1.0-1.6 hours without TSPs.

    Conclusions:

    • The evaluated insulated container system effectively moderates temperature changes in platelet components.
    • Temperature stabilizing packs substantially improve the thermal performance of the shipping system.
    • The system is user-friendly, durable, environmentally sound, and meets freight carrier requirements.