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Multiple myeloma with monoclonal surface immunoglobulin expression: a case report
C H Dunphy1, L M Galindo, W S Velasquez
1Department of Pathology, St. Louis University Health Sciences Center, Missouri, USA.
Acta Cytologica
|March 1, 1996
Summary
Multiple myeloma typically lacks surface immunoglobulin expression on plasma cells. This rare case highlights monoclonal surface immunoglobulin expression, prompting further investigation into its clinical significance.
Area of Science:
- Hematology
- Oncology
- Immunology
Background:
- Normal plasma cells usually lack surface immunoglobulin (sIg).
- Multiple myeloma (MM) plasma cells typically share this immunophenotype.
- Previous studies indicate a lack of sIg expression in MM.