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Related Experiment Videos

Increased bronchial responsiveness in workers sawing Scots pine

P O Malmberg1, A Rask-Andersen, K A Larsson

  • 1National Institute of Occupational Health, Solna, Sweden.

American Journal of Respiratory and Critical Care Medicine
|March 1, 1996
PubMed
Summary

Swedish sawmill workers exposed to agents in the sawing area showed increased bronchial responsiveness and reduced pulmonary function. This study investigated lung health in workers not exposed to red wood cedar asthma triggers.

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Area of Science:

  • Occupational Health
  • Pulmonary Medicine
  • Environmental Exposure

Background:

  • Sawmill workers may be exposed to airborne agents distinct from known sensitizers like plicatic acid.
  • Previous studies have linked wood dust exposure to respiratory issues, but specific agents in sawmills require further investigation.

Purpose of the Study:

  • To assess bronchial responsiveness and pulmonary function in Swedish sawmill workers.
  • To compare respiratory health outcomes among sawyers, trimmers, and referent workers.
  • To investigate the role of sawmill fungi antibodies in relation to lung function.

Main Methods:

  • Measured bronchial responsiveness, transfer factor, and spirometry in 164 sawmill workers.
  • Collected serum for precipitating antibodies against sawmill fungi.

Related Experiment Videos

  • Compared data between sawyers (n=59), trimmers (n=66), and sawyer-referents (n=39).

    • Main Results:

    • Sawyers exhibited significantly higher bronchial responsiveness compared to referents.
    • For sawyers, forced expiratory volume in 1 second (FEV1) decreased by 20% or more with methacholine challenge (55% vs. 31% of referents).
    • Sawyers showed a 13% lower transfer test result than trimmers, indicating reduced diffusion capacity.

    Conclusions:

    • Agents present in the sawing area of sawmills may increase bronchial responsiveness.
    • Exposure to specific sawmill agents appears to decrease pulmonary diffusion capacity.
    • Antibodies to sawmill fungi were not associated with observed pulmonary function changes.