Diseases sometimes associated with psoriasis. I. Candidosis

Area of Science:

• Dermatology
• Immunology
• Genetics

Background:

• Psoriasis (Ps) and candidosis (Cn) are distinct conditions.
• The co-occurrence and familial relationship of these diseases are not well-established.

Purpose of the Study:

• To investigate the association between psoriasis and candidosis.
• To explore potential shared etiological factors.

Main Methods:

• Retrospective analysis of 5,033 patient records from 1968-1975.
• Epidemiological data collection on psoriasis and candidosis prevalence.
• Family history assessment for co-occurrence of diseases.

Main Results:

• 407 patients had psoriasis, and 245 had candidosis.
• A statistically significant number of 38 patients (p < 0.001) presented with both psoriasis and candidosis.
• An additional 24 families showed members with either psoriasis or candidosis, suggesting familial clustering.

Conclusions:

• There is a significant association between psoriasis and candidosis.
• The findings suggest a potential shared genetic or immunological basis for these two conditions.
• Further research is warranted to elucidate the underlying mechanisms linking psoriasis and candidosis.