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Tumor necrosis factor as marker for monocyte function in chronic myeloid leukemia
V S Chitnis1, P M Parikh, J S Nadkarni
1Division of Laboratory Medicine, Tata Memorial Hospital, Bombay, India.
Cancer Investigation
|January 1, 1996
Abstract:
The intactness of monocyte function in chronic myeloid leukemia (CML) patients as assessed by their ability to secret tumor necrosis factor was evaluated. Monocytes from CML patients continued to respond to lipopolysaccharide (LPS) stimulation even during the refractory period, suggesting different pathways for stimulation by LPS and malignant processes.