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Updated: Jul 12, 2026

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Orthotopic Hind-Limb Transplantation in Rats
Published on: July 12, 2010
Major limb amputation in adults, Zaria, Nigeria
A Yakubu1, I Muhammad, O A Mabogunje
1Department of Surgery, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.
Summary
Most limb amputations in Nigeria were preventable, often resulting from trauma or chronic ulcers. Early fracture management and wound care are crucial to avoid these life-altering procedures.
Area of Science:
- Surgical outcomes
- Public health interventions
- Limb amputation epidemiology
Background:
- Limb amputations represent a significant surgical burden in many regions.
- Understanding the primary indications for amputation is vital for preventative strategies.
Purpose of the Study:
- To analyze the indications and outcomes of limb amputations over a decade.
- To identify key areas for preventative interventions in Nigeria.
Main Methods:
- Retrospective review of 320 adult limb amputations.
- Data collection on patient demographics and amputation indications.
- Analysis of treatment and prosthesis fitting rates.
Main Results:
- Trauma and post-fracture gangrene were the leading causes for upper limb amputations (57%).
- Advanced squamous cell carcinoma was the primary indication for lower limb amputations.
- Peripheral vascular disease was rare, except for diabetic ulcers; prosthesis fitting was uncommon.
Conclusions:
- A majority of these amputations were preventable.
- Emphasizes the need for timely fracture management and effective treatment of chronic leg ulcers.
- Highlights the potential for reducing amputation rates through improved healthcare access and early intervention.
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