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Acute isoniazid intoxication: a case report

Y D Chang¹, C C Yang, T J Lin

¹Primary Care Medical Department, Chang-Gung Memorial Hospital, Tao-Yuan, R.O.C.

Zhonghua Yi Xue Za Zhi = Chinese Medical Journal; Free China Ed

|February 1, 1996

Summary

This summary is machine-generated.

Isoniazid overdose can cause severe symptoms like seizures and coma. Prompt recognition and treatment are crucial, especially in regions with high tuberculosis rates, to manage this poisoning effectively.

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Area of Science:

Clinical Toxicology
Pharmacology
Infectious Diseases

Background:

Isoniazid is a primary drug for tuberculosis treatment and prophylaxis since 1952.
Acute isoniazid ingestion can lead to severe toxicity, including seizures, metabolic acidosis, and coma.
Physicians in Taiwan may not fully recognize isoniazid poisoning symptoms despite high tuberculosis prevalence.